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Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma
EtOH up to 100 mM
AK-7 was used at 10-25 µM in vitro and in cellular assays
(1998) Bioorg Med Chem Lett
GNF4877 and its analog GNF7156 are the good chemical tools to support the feasibility of treating diabetes with an oral therapy to restore β-cell mass
CHIR99021 - GSK3β Inhibitor. CAS# 252917-06-9 Catalog No.:M60002-25S Inhibition of histone deacetylase 3CHIR99021, CAS No. 252917 06 9, is the most widely used, potent and selective inhibitor of glycogen synthase kinase 3 (GSK3) with an IC50 ~7 nM. It can effectively activate Wnt signaling pathway in various cellular systems. CHIR99021 has been shown to enhance the reprogramming of murine and human somatic cells into iPSCs, potently promote expansion of embryonic stem cells and tissue specific adult stem cells (such as hematopoietic stem and progenitor
US$ 500000.00
US$ 446868.47
US$ 446868.47