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16(2):134-40
1936468-29-9 (GSK5182 (HCl))
and reactivation from latency
InChiKey: ZNSIZMQNQCNRBW-UHFFFAOYSA-N
29(1):90-102
MK591 xacin(DU 6859A) 16(2):134-40Quiflapon, also known as MK 0591, is a potent and selective 5 Lipoxygenase activating protein (FLAP) inhibitor. MK 0591 is also a potent inhibitor of leukotriene (LT) biosynthesis in intact human and elicited rat polymorphonuclear leukocytes (PMNLs) (IC50 values 3. 1 and 6. 1 nM, respectively) and in human, squirrel monkey, and rat whole blood (IC50 values 510, 69, and 9 nM, respectively). MK 0591 has a high affinity for 5 lipoxygenase activating
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