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single oral administration of ASP9521 suppressed AD-induced intratumoural testosterone production in a dose-dependent manner
anti-infammatory
by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure
InChiKey: CDAPNKYCFHFSNZ-UHFFFAOYSA-N
Treatment of human pancreatic cancer cells with CBL0137 hydrochloride results in a dose dependent reduction of protein and mRNA levels of RRM1 and RRM2
Lei-Dab7 TFA ximab single oral administration of ASP9521Lei Dab7 TFA is a high affinity, selective KCa2. 2 (SK2) channel blocker (Kd=3. 8 nM). Lei Dab7 TFA exhibits >200 fold selectivity for KCa2. 2 over KCa2. 1, KCa2. 3, KCa3. 1, Kv and Kir2. 1. Lei Dab7 TFA increases theta burst responses and increases LTP in rat hippocampal slices in vitro. Product information Molecular Weight: 3508. 10 Formula: C143H239F3N46O41S6 Chemical Name: (3S, 6S, 9S, 12R, 15S, 18S, 21S, 27S, 30S, 36S, 39R, 42S, 48S) 48 (((S) 6
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