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6-(4-fluorophenyl)-2
Smiles: COC1C=C2OC(=O)C=CC2=CC=1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
InChi: InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6
1-7H3/t28-
Target: dopamine D2 receptor
CPI-1189 Catalog No.:M23038-C 6-(4-fluorophenyl)-2CPI 1189 is a proapoptotic cytokine tumor necrosis factor (TNF) alpha inhibitor. AIDS dementia complex is characterized by increased gliosis, apoptosis, and oxidative stress in the CNS, as well as a compromised blood brain barrier. TNF alpha has been reported to be elevated in AIDS dementia complex brains and may contribute to AIDS dementia complex. In vitro: CPI 1189 could potently inhibit p38 MAPK phosphorylation displaying protective action against
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