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56(2):427-36
Competition studies of NCT-503 against 3-phosphoglycerate (3-PG) and the co-substrate NAD+ reveal a non-competitive mode of inhibition with respect to both 3-PG and NAD+
Smiles: CC1=CN([C@H]2C[C@H](O)[C@@H](COC(C3=CC=CC=C3)(C3=CC=C(C=C3)OC)C3=CC=C(C=C3)OC)O2)C(=O)N=C1NC(=O)C1=CC=CC=C1
BSEP induction above vehicle (DMSO) control is observed at concentrations as low as 1 nM
CAS Number: 1865733-40-9
Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C 56(2):427-36EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor . EGFR dimerization stimulates its intrinsic intracellular protein tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues on the C terminal domain of EGFR occurs. These include Y992, Y1045, Y1068, Y1148 and Y1173. This
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