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A concentration-dependent inhibitory effect is observed with IC50 of 454 nM
Smiles: CC1=CC=CC(NC(=O)C=C)=C1NC1=NC2=CC=C(C=C2C=N1)C1C(Cl)=C(C=C(OC)C=1Cl)OC
Int J RadiatOncol Biol Phys
InChi: InChI=1S/C23H22N8O
Formula: C9H9Cl2N3O
MAO-IN-M30 dihydrochloride rdU A concentration-dependent inhibitory effect isMAO IN M30 dihydrochloride is an orally active, brain permeable, and brain selective irreversible MAO A (IC50=37 nM) and MAO B (IC50=57 nM) inhibitor. MAO IN M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO IN M30 dihydrochloride has a neuroprotective effect against Dexamethasone induced brain cell apoptosis. MAO IN M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's