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orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2
used to treat HIV infection
GSK-872 inhibits TNF- and virus-induced necrosis in 3T3-SA fibroblasts
PubMed PMID: 23968981
43 μM) and causes altered cell cycle progression most clearly revealed under conditions of recovery from serum starvation
PNPP Size:Solid 2 mg orally available and ATP-competitive inhibitorpNPP is a non specific phosphatase substrate. Product information CAS Number: 4264 83 9 Molecular Weight: 263. 05 Formula: C6H4NNa2O6P Chemical Name: (4 nitrophenoxy)phosphonic acid sodium Smiles: [Na+].[Na+].[O ][N+](=O)C1C=CC(=CC=1)OP([O ])([O ])=O InChiKey: VIYFPAMJCJLZKD UHFFFAOYSA L InChi: InChI=1S C6H6NO6P. 2Na c8 7(9)5 1 3 6(4 2 5)13 14(10,11)12;; h1 4H,(H2,10,11,12);; q; 2*+1 p 2 Technical Data Appearance: Solid Power Purity: 98% (or refer to