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Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0
InChi: InChI=1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9
orally bioavailable and well tolerated pan-Pim kinase inhibitor
with a half-maximal inhibition at 20 s
GDC-0276 has the potential for the treatment of pain and to address shortcomings of existing pain medications
Baccatin III 19346 Indirubin Derivative E804 also inhibitsBaccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Product information CAS Number: 27548 93 2 Molecular Weight: 586. 63 Formula: C31H38O11 Chemical Name: (1S,2S,3R,4S,7R,9S,10S,12R,15S) 4,12 bis(acetyloxy) 1,9,15 trihydroxy 10,14,17,17 tetramethyl 11 oxo 6 oxatetracyclo[11. 3. 1. 0,. 0,]heptadec 13 en 2 yl