Tipiracil Hydrochloride Catalog No.:M9551-10 10-tetrahydroxy-6a

10-tetrahydroxy-6a

SW033291 was used at 1 µM in vitro and cellular assays

2015 Oct 8

Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2

Smiles: CC1C=CC(=CC=1)C1=NN(C2=NC=NC(N)=C12)C(C)(C)C

Tipiracil Hydrochloride Catalog No.:M9551-10 10-tetrahydroxy-6aTipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS 102, which is an anticancer drug candidate currently in clinical trials. TAS 102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down