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KU-0063794 induces a dose-dependent inhibition of the activity and phosphorylation of Akt at Ser473 and unexpected Thr308 as well as the phosphorylation of the Akt substrates PRAS40 at Thr246
InChi: InChI=1S/C6H8O7/c7-3(8)1-6(13
and excretion
InChi: InChI=1S/C25H27F3N6O3/c1-16-21(31-17(2)35)4-3-5-22(16)32-23-29-15-30-24(33-23)34-12-10-19(11-13-34)36-14-18-6-8-20(9-7-18)37-25(26
Midecamycin is a 16-membered macrolide
XL-784 Size:Contact [email protected] for quotation KU-0063794 induces a dose-dependent inhibitionXL 784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0. 81, 120, 10. 8, 18, 0. 56 nM for MMP 1MMP 2MMP 3MMP 8MMP 9MMP 13respectively. Product information CAS Number: 1224964 36 6 Molecular Weight: 561. 07 Formula: C42H42Cl2F4MgN6O16S2 Chemical Name: magnesium(2+) bis(({1 [4 (4 chlorophenoxy) 3,5 difluorobenzenesulfonyl] 4 [(2 methoxyethoxy)carbonyl]piperazin 2 yl}formamido)olate) Smiles: [Mg+2]. COCCOC(=O)N1CC(C(=O)N[O
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