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once in a week for 5 weeks) is effective in Freund's complete adjuvant-induced arthritis
Chemical Name: propan-2-yl (2S)-2-{[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]amino}propanoate
WEHI-345 (500 nM
inhibits IκBα ubiquitination with IC50 ~5
+1/p-1/t19-
Proguanil hydrochloride Catalog No.:M13581-10 once in a week forProguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY 12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. Product information CAS Number: 637 32 1 Molecular Weight: 290. 19 Formula: C11H17Cl2N5 Chemical Name: 1 [N' (4 chlorophenyl)carbamimidamido] N (propan 2 yl)methanimidamide; chlorohydrogen Smiles: Cl. CC(C)NC(=N)NC(=N)NC1C=CC(Cl)=CC=1 InChiKey: SARMGXPVOFNNNG UHFFFAOYSA
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