Dasatinib N-oxide - CAS# 910297-52-8 guat InChi: InChI=1S/C23H24ClN3O3/c24-18-7-8-19-20(14-18)25-16-27(22(19)29)15-23(30)10-12-26(13-11-23)21(28)9-6-17-4-2-1-3-5-17/h1-5

InChi: InChI=1S/C23H24ClN3O3/c24-18-7-8-19-20(14-18)25-16-27(22(19)29)15-23(30)10-12-26(13-11-23)21(28)9-6-17-4-2-1-3-5-17/h1-5

the A66 on SK-OV-3 tumour tissue is tested using a single dose of 100 mg/kg of body weight to determine whether a long-lasting effect of the drug could be achieved on target tissues

C[N+]1(C)[C@@H]2C[C@H](C[C@H]1[C@@H]1O[C@@H]12)OC(=O)[C@H](CO)C1C=CC=CC=1

this agent is readily taken up by pancreatic beta cells

It causes growth inhibition of normal and transformed cells but does not induce cell death

Dasatinib N-oxide - CAS# 910297-52-8 guat InChi: InChI=1S/C23H24ClN3O3/c24-18-7-8-19-20(14-18)25-16-27(22(19)29)15-23(30)10-12-26(13-11-23)21(28)9-6-17-4-2-1-3-5-17/h1-5Dasatinib N oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src Bcr Abl inhibitor. Product information CAS Number: 910297 52 8 Molecular Weight: 504. 00 Formula: C22H26ClN7O3S Chemical Name: 4 [6 ({5 [(2 chloro 6 methylphenyl)carbamoyl] 1,3 thiazol 2 yl}amino) 2 methylpyrimidin 4 yl] 1 (2 hydroxyethyl)piperazin 1 ium 1 olate Smiles: CC1N=C(C=C(NC2=NC=C(S2)C(=O)NC2=C(Cl)C=CC=C2C)N=1)N1CC[N+]([O ])(CCO)CC1