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Epub 2010 May 11
reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE)
cell proliferation and differentiation
InChiKey: AFJYYKSVHJGXSN-VOMYPSQFSA-N
2019 May 26
Butein - CAS# 487-52-5 Catalog No.:M12193-10 Epub 2010 May 11Butein, isolated from Dalbergia odorifera T. Chen, is a cAMP specific PDE inhibitor with an IC50 of 10. 4 M for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 M for EGFR and p60c src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator (STAC). Product information CAS Number: 487 52 5 Molecular Weight: 272. 25 Formula:
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