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Clodronate disodium tetrahydrate 3-N3 InChi: InChI=1S/C15H9N5O/c1-2-21-20-14-10-6-4-3-5-9(10)13-15(14)19-12(8-17)11(7-16)18-13/h3-6H

SKU: 93746002491

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Description

InChi: InChI=1S/C15H9N5O/c1-2-21-20-14-10-6-4-3-5-9(10)13-15(14)19-12(8-17)11(7-16)18-13/h3-6H

First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway

CAS Number: 1309283-24-6

Formula: C15H31NO2

Chemical Name: 2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate

Clodronate disodium tetrahydrate 3-N3 InChi: InChI=1S/C15H9N5O/c1-2-21-20-14-10-6-4-3-5-9(10)13-15(14)19-12(8-17)11(7-16)18-13/h3-6HClodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first generation bisphosphonate, with anti osteoporotic, anti inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15. 6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and

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