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IBT6A (Compound 14) can be used in synthesis of Ibrutinib and Ibrutinib-based activity-based probes (ABPs)
which is a pro-apoptotic BCL-2 family member
2015 May 6
InChiKey: XZAFZXJXZHRNAQ-STQMWFEESA-N
Holzhauer B
EEDi-5285 Catalog No.:M16781-C IBT6A (Compound 14) can beEEDi 5285 is an exceptionally potent and orally active embryonic ectoderm development (EED) inhibitor with an IC50 value of 0. 2 nM for binds to the EED protein. EEDi 5285 has anti cancer activity. Product information CAS Number: 2488952 40 3 Molecular Weight: 479. 53 Formula: C24H22FN5O3S Chemical Name: 8 (6 cyclopropylpyridin 3 yl) N [(5 fluoro 2,3 dihydro 1 benzofuran 4 yl)methyl] 1 methanesulfonylimidazo[1,5 c]pyrimidin 5 amine Smiles: