Leelamine hydrochloride atadine-d9 7 nM for hA1AR and

7 nM for hA1AR and hA3AR

2019 Oct 30:1-7

CAS Number: 169545-27-1

Smiles: CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCN=[N+]=[N-]

whereas the IC50s of Y-27632 and Y-33075 for CaMKII is 236 and 225 times those for ROCK

Leelamine hydrochloride atadine-d9 7 nM for hA1AR andLeelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1 regulated fatty acid lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].