![Palovarotene - CAS# 410528-02-8 Size:Solid 10 mg Smiles: COC1=CC=C(CNC2=NC(=NC=C2C(=O)NCC2N=CC=CN=2)N2CCC[C@H]2CO)C=C1Cl](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10349_1621561737.gif?v=1742880941)
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Smiles: COC1=CC=C(CNC2=NC(=NC=C2C(=O)NCC2N=CC=CN=2)N2CCC[C@H]2CO)C=C1Cl
16-tetramethyl-8
glutathione level
5(19):9382-95
InChi: InChI=1S/C22H24O6/c1-11-5-13-7-15-19(27-9-25-15)21(23-3)17(13)18-14(6-12(11)2)8-16-20(22(18)24-4)28-10-26-16/h7-8
Palovarotene - CAS# 410528-02-8 Size:Solid 10 mg Smiles: COC1=CC=C(CNC2=NC(=NC=C2C(=O)NCC2N=CC=CN=2)N2CCC[C@H]2CO)C=C1ClPalovarotene, also known as RO 3300074 and R 667, is a highly selective retinoic acid receptor gamma (RAR ) agonist that is under investigation as a potential treatment for emphysema. Phase I clinical trials of palovarotene in patients with emphysema demonstrated that the drug is well tolerated, with improvements observed in markers of emphysema progression. Emphysema is characterized by the destruction of alveoli and alveolar ducts within the lungs.
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