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GANT58 is a cell-permeable tetrapyridinylthiophene compound that acts as downstream Hedgehog (Hh) pathway blocker and targets Gli-mediated gene transactivation (IC50 ~ 5 µM in SAG-stimulated Shh-L2 cells)
Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway
BETP also potentiates cAMP production of the dual-acting GLP-1R/glucagon (GCG) receptor (GCGR) agonist oxyntomodulin at GLP-1R
and N-methyl-(R)-salsolinol
MGCD0103 at 80 mg/kg (free base) almost completely blocks the growth of H1437 tumors after 13 days of daily p
Thalidomide-NH-PEG3-CH2CHO - CAS# 2360530-43-2 Catalog No.:M11569-2 GANT58 is a cell-permeable tetrapyridinylthiopheneThalidomide NH PEG3 CH2CHO is the Thalidomide based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide NH PEG3 CH2CHO can be connected to the ligand for protein by a linker to form PROTAC BCL XL degrader XZ739 (HY 133557). Product information CAS Number: 2360530 43 2 Molecular Weight: 447. 44 Formula: C21H25N3O8 Chemical Name: 2 {2 [2 (2 {[2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 4