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Netupitant metabolite Monohydroxy Netupitant Catalog No.:M8234-10 Two indolocarbazole alkaloids with apoptosis

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Description

Two indolocarbazole alkaloids with apoptosis activity from a marine-derived actinomycete Z2039-2 Arch

Appearance: White to Off-White Solid

InChi: InChI=1S/C31H41NO4/c1-26(2)10-12-31(25(35)36)13-11-30(7)23(19(31)16-26)20(33)14-22-28(5)15-18(17-32)24(34)27(3

in contrast with the 100 mg/kg dose

b-AP15 was used at 10 µM final concentration in various in vitro assays

Netupitant metabolite Monohydroxy Netupitant Catalog No.:M8234-10 Two indolocarbazole alkaloids with apoptosisMonohydroxy Netupitant is the metabolite of Netupitant which is a potent and selective neurokinin 1 receptor (NK1) receptor antagonist. It is achiral and orally active. Product information CAS Number: 910808 12 7 Molecular Weight: 594. 59 Formula: C30H32F6N4O2 Synonym: Monohydroxy Netupitant Chemical Name: 2 [3,5 bis(trifluoromethyl)phenyl] N {4 [2 (hydroxymethyl)phenyl] 6 (4 methylpiperazin 1 yl)pyridin 3 yl} N,2 dimethylpropanamide Smiles:

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