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All by itself, a 2/2 with vigilance that can tap for two mana is already borderline playable in Commander, but in a deck with three or more colors the card just gets bonkers

The same is true for any counters that change its power and/or toughness

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The intended combos to win are between Gisa and creatures that can be given high power such as Soulless One (power = # of zombies in play and graveyard) or Unbreathing Horde (same as Soulless One) as both them can have high power which can be converted in large numbers of 2/2 zombie tokens by Gisa then brought back in play with even greater power, rinse and repeat

Shrouded Fable is an interesting case when it comes to hits as it's one of very few sets where energy cards and items are prominent in the top of the top